Bifine Cream is used to treat fungal skin infections like jock itch, ringworm, and athlete's foot. It is a member of antifungal agents and inhibits fungus growth in order to work. As instructed by a healthcare professional, the cream is applied to the affected area of the skin and the surrounding areas once or twice daily for a specific amount of time. Bifine Cream is safe to use. The severity of the infection and how well the patient responds to the medication will determine how long the treatment will last.