Peg L Asparaginase injection

1 INR/Pack

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Peg L Asparaginase injection Price And Quantity

Supply Ability Per Day
Delivery Time 30-60 Days
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Main Export Market(s) Australia North America Eastern Europe Western Europe Middle East Central America South America Asia Africa
Main Domestic Market All India
Certifications USFDA

Warnings:

Contraindications
Hypersensitivity
History of (with prior L-asparaginase treatment): pancreatitis; hemorrhagic events; serious thrombosis

Cautions:

No more than 2ml should be administered at any one injection site
Anaphylaxis or serious allergic reactions may occur, monitor patient for 1 hr after administration; discontinue with serious allergic reactions
Glucose intolerance reported (irreversible in some cases); monitor serum glucose
Hepatotoxicity and abnormal liver function, including elevations of AST (SGOT), ALT (SGPT), alkaline phosphatase, bilirubin (direct and indirect), and depression of serum albumin, and plasma fibrinogen may occur; monitor

Discontinue if pancreatitis occurs; evaluate patients with abdominal pain for pancreatitis
Serious thrombotic events, including sagittal sinus thrombosis reported; discontinue if this occurs
Increased prothrombin time, increased PTT and hypofibrinogenemia may occur; monitor for coagulopathy

Pregnancy & Lactation

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

Pharmacology

Mechanism of Action
Modified version of L-asparaginase depletes asparagine, the aminoacid required for protein synthesis, and in turn kills leukemic cells

Pharmacokinetics

Warnings:

Specification

Brand Name	Peg L-Asparkay
Best Before	24 months from Manufacture date
Form Of Medicine	Injection
Grade	Medicine Grade
Storage	Store in cool and dry place
Packaging Size	5 ml